Protein Info for PS417_03010 in Pseudomonas simiae WCS417

Annotation: XRE family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 447 transmembrane" amino acids 18 to 41 (24 residues), see Phobius details amino acids 50 to 72 (23 residues), see Phobius details amino acids 94 to 118 (25 residues), see Phobius details amino acids 140 to 159 (20 residues), see Phobius details amino acids 167 to 187 (21 residues), see Phobius details amino acids 193 to 213 (21 residues), see Phobius details amino acids 247 to 266 (20 residues), see Phobius details amino acids 277 to 297 (21 residues), see Phobius details amino acids 317 to 343 (27 residues), see Phobius details amino acids 359 to 380 (22 residues), see Phobius details amino acids 392 to 409 (18 residues), see Phobius details amino acids 415 to 435 (21 residues), see Phobius details TIGR00797: MATE efflux family protein" amino acids 23 to 416 (394 residues), 254.1 bits, see alignment E=1.1e-79 PF01554: MatE" amino acids 23 to 183 (161 residues), 82.5 bits, see alignment E=1.4e-27 amino acids 248 to 405 (158 residues), 50 bits, see alignment E=1.4e-17

Best Hits

KEGG orthology group: K03327, multidrug resistance protein, MATE family (inferred from 96% identity to pfs:PFLU0628)

Predicted SEED Role

"DNA-damage-inducible protein F"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U6E2 at UniProt or InterPro

Protein Sequence (447 amino acids)

>PS417_03010 XRE family transcriptional regulator (Pseudomonas simiae WCS417)
MPTLLTDWRHRPTHRRVWALAAPMILSNISVPLVALVDSMVIGHLPHAHQLGAVAVGASL
YTFLAWAMGFLRMGSTGFAAQAAGRNDGAALRQILLQGLLLALGLAMLLGTVGIPLSHLA
LEWMQPSPELNQLTQDFFHTRLFGLPAALASYALVGWFLGTQNARAPLAILLTTNLVNIA
LNLWFVLGLDWGVVGSARASVVAEWTGALLGLAMTQKALRAYPGHIAWAALKWWASWRPL
LAVNRDIFIRSLALQSVFFMITVQGARLGDATVAANALLLNGLLLTAHALDGLAHAVEAL
CGHAIGAHDRQALRRSLVVAGGWSLIASVGFALLFTVAGHLFIAMQTDIPSVRETADIYL
PYLAVLPLIAVWSYLLDGLFIGATRAREMRNGMLLTVVLVLPIAWALQGLGNHGLWITFL
VFMTVRSLTLWAIAWRLNRQGLWLGSS