Protein Info for GFF5886 in Variovorax sp. SCN45

Annotation: Transcription antitermination protein NusG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 203 PF02357: NusG" amino acids 30 to 133 (104 residues), 105.9 bits, see alignment E=1.3e-34 TIGR00922: transcription termination/antitermination factor NusG" amino acids 31 to 202 (172 residues), 227.7 bits, see alignment E=4e-72 PF00467: KOW" amino acids 152 to 182 (31 residues), 28.9 bits, see alignment 7.4e-11

Best Hits

Swiss-Prot: 66% identical to NUSG_NEIMB: Transcription termination/antitermination protein NusG (nusG) from Neisseria meningitidis serogroup B (strain MC58)

KEGG orthology group: K02601, transcriptional antiterminator NusG (inferred from 98% identity to vap:Vapar_0583)

Predicted SEED Role

"Transcription antitermination protein NusG" in subsystem Transcription factors bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

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Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (203 amino acids)

>GFF5886 Transcription antitermination protein NusG (Variovorax sp. SCN45)
MTDDAVETTPSTPEEENTSVLAPAANPDLRWYVVHAYSGMEKAVERNITERINRAGMQDK
FGRILVPTEEVVEIKNGQKRTTERRFFPGYVLVEMIMDDESWHLVKHTNKVTGFVGGAKN
RPAPISQKEVEDIVSQMQQGTEKPRHKVEFTVGEFVRVKEGPFTDFNGTVEEVNYEKSKV
SVSVMIFGRATPVELEFSQVEKT