Protein Info for GFF562 in Xanthobacter sp. DMC5

Annotation: Protein-export membrane protein SecF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 369 transmembrane" amino acids 21 to 42 (22 residues), see Phobius details amino acids 137 to 157 (21 residues), see Phobius details amino acids 164 to 185 (22 residues), see Phobius details amino acids 191 to 212 (22 residues), see Phobius details amino acids 233 to 259 (27 residues), see Phobius details amino acids 267 to 293 (27 residues), see Phobius details PF07549: Sec_GG" amino acids 36 to 61 (26 residues), 34.8 bits, see alignment (E = 8.8e-13) TIGR00966: protein-export membrane protein SecF" amino acids 41 to 286 (246 residues), 267.1 bits, see alignment E=1.7e-83 TIGR00916: protein-export membrane protein, SecD/SecF family" amino acids 98 to 283 (186 residues), 189.6 bits, see alignment E=6.4e-60 PF02355: SecD_SecF_C" amino acids 117 to 294 (178 residues), 215.1 bits, see alignment E=5.7e-68

Best Hits

KEGG orthology group: K03074, preprotein translocase subunit SecF (inferred from 85% identity to xau:Xaut_4310)

Predicted SEED Role

"Protein-export membrane protein SecF (TC 3.A.5.1.1)" (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (369 amino acids)

>GFF562 Protein-export membrane protein SecF (Xanthobacter sp. DMC5)
MPLIDYIPAQTNIHFMRLRHWTFPFSAALSIVACLLFAIHGFNLGIDFKGGTLIEAQTSQ
QQADIGALREHLTDLDVGDVQIQEFGSPRDVLIRIGAFGTTDEAQQAILAKVQGVLGTDY
SVRRVETVGPSVSGELVRQSILALVLGAVAVLGYLWFRFEWQFAVGAIVTTMHDIFVTLM
IYSAFGIDFDLTSIAAILTIMGYSLNDTVVVYDRIREMLRRYKKLPLPELLDIAVNATFS
RTIIVSTTTFFATLALYFFGGEVLRGFSLAMTVGVVIGTYSTIFVAAPILIHLGLRASTV
SLPTKDAADPEVKELDELVKLEAKDAAAGVPPEAAPATGVSAGGGSNKSGKGKNGKPNGK
AGPARPAKA