Protein Info for GFF56 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Eight transmembrane protein EpsH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 287 transmembrane" amino acids 6 to 30 (25 residues), see Phobius details amino acids 37 to 55 (19 residues), see Phobius details amino acids 66 to 84 (19 residues), see Phobius details amino acids 90 to 109 (20 residues), see Phobius details amino acids 118 to 138 (21 residues), see Phobius details amino acids 173 to 198 (26 residues), see Phobius details amino acids 210 to 234 (25 residues), see Phobius details amino acids 246 to 270 (25 residues), see Phobius details TIGR03113: exosortase B" amino acids 8 to 272 (265 residues), 402.5 bits, see alignment E=1.5e-124 PF09721: Exosortase_EpsH" amino acids 13 to 269 (257 residues), 225.8 bits, see alignment E=3e-71 TIGR02602: exosortase" amino acids 30 to 270 (241 residues), 132 bits, see alignment E=3.9e-42 TIGR04178: exosortase/archaeosortase family protein" amino acids 176 to 268 (93 residues), 63.1 bits, see alignment E=3.6e-21

Best Hits

KEGG orthology group: None (inferred from 67% identity to app:CAP2UW1_0838)

Predicted SEED Role

"Eight transmembrane protein EpsH"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (287 amino acids)

>GFF56 Eight transmembrane protein EpsH (Hydrogenophaga sp. GW460-11-11-14-LB1)
MVARLLPWLPIMVGLAVLYVPTLYDLFTGIWAQDDQFHGPIVLAIALWLMHRNWGAMEAA
ALGQKTSAWGWPLVVVALMFYALGRSQGMGILEVGSVIWLLAGVILLTRGTAGLKAQWFA
LFFMLFMVPLPSQVVDLVTMPMKMMVSYVAENVLYALGYPIGRNGVILQIGQYMLLVADA
CAGLHTLLTLEALGLLYLNLVRRDSLFRNVALAVLIVPISFTANVIRVMALSLITYHFGN
EAGQGFLHGFAGMVLFLSALLMIIAFDSALQAVERLRQRHNPSLQKA