Protein Info for GFF557 in Xanthobacter sp. DMC5

Annotation: Sec-independent protein translocase protein TatC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 269 transmembrane" amino acids 28 to 48 (21 residues), see Phobius details amino acids 82 to 104 (23 residues), see Phobius details amino acids 117 to 142 (26 residues), see Phobius details amino acids 167 to 194 (28 residues), see Phobius details amino acids 207 to 223 (17 residues), see Phobius details amino acids 229 to 249 (21 residues), see Phobius details TIGR00945: twin arginine-targeting protein translocase TatC" amino acids 14 to 239 (226 residues), 203.1 bits, see alignment E=2.6e-64 PF00902: TatC" amino acids 16 to 234 (219 residues), 235.6 bits, see alignment E=2.6e-74

Best Hits

Swiss-Prot: 46% identical to TATC_MAGMM: Sec-independent protein translocase protein TatC (tatC) from Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1)

KEGG orthology group: K03118, sec-independent protein translocase protein TatC (inferred from 92% identity to xau:Xaut_4405)

Predicted SEED Role

"Twin-arginine translocation protein TatC" in subsystem Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related or Twin-arginine translocation system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (269 amino acids)

>GFF557 Sec-independent protein translocase protein TatC (Xanthobacter sp. DMC5)
MSDQDEIDASKAPLIEHLIELRSRLIKSLVAFLVAFIACFMLAKQIYNILLWPYEFASGF
GTGVKLIYTAPQEFLFTQIKLGMFGAAFISFPVVATQVYMFVAPGLYKHEKAAFRPYLVA
TPICFLIGAAFVYFVAMPLAMTYFLGMQQVGGDGKAEISLLPRVSEYLSLITTLILAFGI
CFQLPVILTLLGQIGVVTREMLVKARRYAIVGVFVLAAVLTPPDVISQLSLALPTLLLYE
VSVYLVGVVEKRRLVAEAARNAADAATAD