Protein Info for PS417_27695 in Pseudomonas simiae WCS417
Annotation: alanine racemase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 87% identical to ALR_PSEF5: Alanine racemase (alr) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
KEGG orthology group: K01775, alanine racemase [EC: 5.1.1.1] (inferred from 94% identity to pfs:PFLU5966)MetaCyc: 80% identical to alanine racemase (Pseudomonas putida)
Alanine racemase. [EC: 5.1.1.1, 5.1.1.10]
Predicted SEED Role
"Alanine racemase (EC 5.1.1.1)" in subsystem Alanine biosynthesis or Pyruvate Alanine Serine Interconversions (EC 5.1.1.1)
MetaCyc Pathways
- L-alanine degradation I (2/2 steps found)
- alanine racemization (1/1 steps found)
- anaerobic energy metabolism (invertebrates, cytosol) (4/7 steps found)
- L-lysine degradation V (5/9 steps found)
- L-arginine degradation XIV (oxidative Stickland reaction) (2/6 steps found)
- superpathway of anaerobic energy metabolism (invertebrates) (9/17 steps found)
- ansatrienin biosynthesis (1/9 steps found)
- cyclosporin A biosynthesis (2/15 steps found)
- superpathway of L-lysine degradation (17/43 steps found)
KEGG Metabolic Maps
- Alanine and aspartate metabolism
- Cysteine metabolism
- D-Alanine metabolism
- D-Arginine and D-ornithine metabolism
- D-Glutamine and D-glutamate metabolism
- Glycine, serine and threonine metabolism
Isozymes
No predicted isozymesUse Curated BLAST to search for 5.1.1.1 or 5.1.1.10
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A1N7UQN4 at UniProt or InterPro
Protein Sequence (357 amino acids)
>PS417_27695 alanine racemase (Pseudomonas simiae WCS417) MRPARALIDLQALRHNYQLAREVTGAKALAVIKADAYGHGAVRVAQALQAEADGFAVACI EEALELRAAGIRAPVLLLEGFFEADELPLIIEHDFWCVVHSLWQLEAIEQAKLSKPLTIW LKLDSGMHRVGLHPKDYHEAYQRLLASGKVAKIVLMSHFARADELDCVRSDEQVAVFDAA RQGLSAEVSLRNSPSVIGWPNVSSDWVRPGIMLYGATPFGEDQAIASRLQPVMTLESKVI CVRELPAGEPVGYGAKFITPKPMRIGVVAMGYADGYPRHAPTGTPVLVAGQRSQLLGRVS MDMLCIDLTDLPQAGLGSTVELWGKNILASDVAVAAETIPYQLFCNLRRVPRLYSEA