Protein Info for PS417_27680 in Pseudomonas simiae WCS417

Annotation: acetyl-CoA hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 640 PF13336: AcetylCoA_hyd_C" amino acids 362 to 524 (163 residues), 129.6 bits, see alignment E=5e-42

Best Hits

KEGG orthology group: None (inferred from 97% identity to pfs:PFLU5963)

Predicted SEED Role

"Acetyl-CoA hydrolase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U386 at UniProt or InterPro

Protein Sequence (640 amino acids)

>PS417_27680 acetyl-CoA hydrolase (Pseudomonas simiae WCS417)
MVQLCSIEQAVDDVLERLPAHIHMGMPLGLGKPNLFANALYRRIAKLPERSLTIYTALSL
GRPTLGDGLQKRFLEPFIERVFGDYPELDFLAALHKDNLPKNIHVQQFFMQPGSLLHSES
AQQDYVSSNYSHAARDINAAGLNLVAQLVASSSEHPDRLSLSCNPDITLDLLPMIAKRRD
AGETVLIVGQVHSDLPYMPGDAELGMDAFDYLIDEKDSTTLFSTPNMPVGFQDHFIGLHA
STLVRDGGTLQIGIGSMGDALTAALLARQADNEAYRLLLTDLDVYQWAPLISHEGGVDPF
ARGLYGCSEMFVNGLLVLADAGIIRRKVYPDVATQQQANAGTLDDAAQPDGISIHGGFFL
GPRSFYQRLQEMTHAKRLEFNMTRISYINELYGQEELKRLQRRDARFINSAIMVTLLGAG
VADQLEDGRVLSGVGGQYNFVAQGHALEGARSILILRSWRESAGEVSSNIVWDYGHCTIP
RHLRDIVITEYGIADLRGQTDAKVIEALLNVTDSRFQNDLIEKAQKAGKLPKDFQLDPRF
ADNTPERLQGIQARHRRLFPEYPLGSDFTDEERDLLRALNWLKSKFKLTEILELGKAALD
APEPEAYPEHLKRMRLDNPEGLKEDLYQRLLLAGLQATVH