Protein Info for GFF5372 in Sphingobium sp. HT1-2

Annotation: Chaperone protein HtpG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 628 PF13589: HATPase_c_3" amino acids 37 to 159 (123 residues), 37.2 bits, see alignment E=3e-13 PF00183: HSP90" amino acids 226 to 626 (401 residues), 335.3 bits, see alignment E=8.2e-104

Best Hits

Swiss-Prot: 66% identical to HTPG_AZOC5: Chaperone protein HtpG (htpG) from Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / NBRC 14845 / NCIMB 13405 / ORS 571)

KEGG orthology group: K04079, molecular chaperone HtpG (inferred from 71% identity to sch:Sphch_0329)

Predicted SEED Role

"Chaperone protein HtpG" in subsystem Protein chaperones

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (628 amino acids)

>GFF5372 Chaperone protein HtpG (Sphingobium sp. HT1-2)
MTIDTVTAPETRAFEADVSKLLHMMVHSVYSDRDVFLRELISNAADACEKLRYEAISNPA
LLGEDPQSRINIRLDKEAGTLVIEDNGIGMTAADMGDTLGTIARSGTKAFMDKLTADKNG
EGQQLIGQFGVGFYSAFMVAGKVEVASRRAGEDDAAIWSSDGLGTYTIAPADPAAAPARG
TRVALHLLDDARTYAERFTVERIIKAQSGHVPVPIFLQEAGSEDEPNQVADGVALWTKAK
SDISEENYADFYRGVAGQFDKPALTLHYRAEGRHEYSVLIFIPETKPFDLFDPDRKGRIK
LYVRRVFITDEAEILPRYLRFVRGLVDSADLPLNMSREMIQDSPVLSAIQKGISNRILSE
LDKLSTSEPERYAAIWENFGSVLKEGLYEDFERREALLGLARFKSTMSDGAWRSLKDYVS
ALKENQTAIYYATGHDLDRLAQSPQIEGFKARGIEVLLLPDQVDSFWTTIGVDYEGKPFK
SVTQGAADLSLIPLADGTSNAATPSEEANSFITFAKKALADQVSDVRISDRLTSSAVCIV
AADNAMDLQLDRMLAAAGRAPERAKPILEVNAGHALIAKLGHASGDEEERRDLAFLLLDE
ARIAEGEAPVDSRAFAERLERLMAKAWG