Protein Info for PS417_27380 in Pseudomonas simiae WCS417

Annotation: GntR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 231 PF00392: GntR" amino acids 12 to 71 (60 residues), 65.2 bits, see alignment E=3.3e-22 PF07729: FCD" amino acids 92 to 215 (124 residues), 96.1 bits, see alignment E=2.2e-31

Best Hits

KEGG orthology group: K05799, GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex (inferred from 96% identity to pfs:PFLU5902)

Predicted SEED Role

"Transcriptional regulator, GntR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UJE6 at UniProt or InterPro

Protein Sequence (231 amino acids)

>PS417_27380 GntR family transcriptional regulator (Pseudomonas simiae WCS417)
MNSIAQAVPEAALQAIRKLIKDQGFGPGDALPSQRDLAVQLGVSRASLREALSSLSALGV
VSVQPGKGVFVQAAEESPGFTWPFAAQATPLDIFQLRYALEGFAAGLAAVTLTVDELDSL
EDNVEAMRKVLKAGDFEAAARLDFEFHQRVLLASGNQAMVSILSASAEVFLESQKLPFIR
PERAMETWQEHRRILRALARRASAAAQKSMQEHVRNAALRTGIAFVTPVTP