Protein Info for PS417_27360 in Pseudomonas simiae WCS417

Annotation: CDP-6-deoxy-delta-3,4-glucoseen reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 322 PF00111: Fer2" amino acids 3 to 70 (68 residues), 39.2 bits, see alignment E=5.4e-14 PF00175: NAD_binding_1" amino acids 197 to 295 (99 residues), 57.4 bits, see alignment E=2.2e-19

Best Hits

KEGG orthology group: K00523, CDP-4-dehydro-6-deoxyglucose reductase [EC: 1.17.1.1] (inferred from 98% identity to pfs:PFLU5897)

Predicted SEED Role

"NAD(P)H-flavin reductase (EC 1.5.1.29) (EC 1.16.1.3)" in subsystem Ubiquinone Biosynthesis (EC 1.16.1.3, EC 1.5.1.29)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.17.1.1, 1.5.1.29

Use Curated BLAST to search for 1.16.1.3 or 1.17.1.1 or 1.5.1.29

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U8I1 at UniProt or InterPro

Protein Sequence (322 amino acids)

>PS417_27360 CDP-6-deoxy-delta-3,4-glucoseen reductase (Pseudomonas simiae WCS417)
MRVTLQPSGAVLELVPGERILEGARRLGYECPQACRNGVCHVCAALLVEGRVQQAGEVRD
HGEFYTCIAEPLEDCIVLWDGVLAPGELPLRKLSCQLSECVEVGGDVWRVRLRAPAGKAV
RYHAGQYLMIERENGEQSAFSLASAPHAGRELELHVLAREDSARTLLAQLQRNQMARVEL
PFGDTHLAELPDGPLVLIAAGTGMAQMHSLIEHCRASGFKHPVHLYWGVRRPEDFYQIEH
WDQWLQLPNLFLHKVVSDLCGWEGRCGLLHEAVCEDIADLKSVHVYASGSPAMIYGTLDA
LVDAGMDAHQMRADVFAYAPRP