Protein Info for GFF5335 in Sphingobium sp. HT1-2

Annotation: Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 817 signal peptide" amino acids 1 to 37 (37 residues), see Phobius details PF07660: STN" amino acids 68 to 113 (46 residues), 33.3 bits, see alignment 5.1e-12 PF07715: Plug" amino acids 167 to 266 (100 residues), 73.6 bits, see alignment E=2.6e-24 TIGR01783: TonB-dependent siderophore receptor" amino acids 169 to 814 (646 residues), 316 bits, see alignment E=3.1e-98 PF00593: TonB_dep_Rec_b-barrel" amino acids 347 to 785 (439 residues), 187.5 bits, see alignment E=1.2e-58

Best Hits

Predicted SEED Role

"TonB-dependent siderophore receptor" in subsystem Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (817 amino acids)

>GFF5335 Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid (Sphingobium sp. HT1-2)
MFGGNSHKMVAGTKALGLLLLASASATMTLAPSAQAQLSGQRSFNIAAQPLTEAIMQFGR
QSGLQVTADTRLVAGKTGAAVSGNHAPAEALSMLLAGTGLTFRFTSRTTAILEPAPHASV
DAVQLGPVRVEGAQGAGLVASSDPGATEGTGSYAPTKVTVGKSAQSLREIPQSVSVITRK
RMDDQNMTTVSEALDQVTGVRSFGYERQEQYIIRGYAANAQYNGVPQQEGSDKASSNTDD
LAFFDRIEVLRGPSGLLTGSGEPGGTINYVRKRPTDVLAIAGLASLGSWDRYRGEIDVGG
PVTASGNLRARIVGVYQDEDKYYDVGFNKDRGIYGVVEYDLTPRTTIGVSGIYSQRKFIN
SFGLPLYDDNSVPARGSFTGSDATSRQRSRELFVDLSHDFGGDWSFKAAYSLRRMDYGGY
SVFPGDAIDRETGLVPSLSAGRVEQETKWHSFDAHVTGPLHLFGRTHDLTFGVNRSRYDF
IGGTKFVNPGAWDVLNDHDLSAIIDENITYRYETVTAQTGFYGSARIRLADPLTIVLGGR
LTNFKIKDRDVVPEVTPWIDSSAKSSGRFTPYAGVVLDVTDQLTLYASYTDTFVPQTAQD
VNNRTLAPRVGWQMETGVKGSFFNDALNASVALFRIHDSNRAIVDEVNVGCGGTIDGTCS
RAAGKVRSQGVEVDIGGSPLPGWDITLGYTYNQQKYLSDTDPTNVGQRFLPAQSPEQMFK
LWTQFDLGKAGVQGWASGLNIGGGVQAQSNMYTDLVRQNAYAIANAKAGYRVSENWDLSL
VVNNLFDRTYLRIPGYAIFYNIYGEPRNFRLTLRGKI