Protein Info for GFF5334 in Sphingobium sp. HT1-2

Annotation: Putative FecR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 324 transmembrane" amino acids 86 to 108 (23 residues), see Phobius details PF16220: DUF4880" amino acids 11 to 52 (42 residues), 42.5 bits, see alignment 4.7e-15 PF04773: FecR" amino acids 113 to 205 (93 residues), 77.1 bits, see alignment E=1.2e-25

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (324 amino acids)

>GFF5334 Putative FecR (Sphingobium sp. HT1-2)
MSDKADHISMEASEWLIRLREAPDDRDLERRFIVWRDADPDHLRAWSEMQALFDLIGDVE
ARHPEYLVPASDPPPAYGASRLRRLWKVTAISAIAACLAILVGPALLLRMQADHMTAAGH
LANIRLDDGSRIHLGPDSAIAVAYSVERRDVRLLKGQAWFEVHPDKSRPFRVRTDRISAT
ALGTAFDVRMIGTDRSVAVGHGRVRIDESARNDSRQAAPKAVLNAGDWIAAVSGKGIDKG
HQASDLAGIWQSGSVIIRGRTVADAIEELRPWYKGRILLANDDVGAKRVTGIYRLSDPEE
ALRALVEPHGGSITRITPWLMIVS