Protein Info for GFF5327 in Variovorax sp. SCN45

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 418 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 48 to 69 (22 residues), see Phobius details amino acids 80 to 100 (21 residues), see Phobius details amino acids 107 to 127 (21 residues), see Phobius details amino acids 145 to 169 (25 residues), see Phobius details amino acids 175 to 194 (20 residues), see Phobius details amino acids 224 to 250 (27 residues), see Phobius details amino acids 256 to 278 (23 residues), see Phobius details amino acids 290 to 309 (20 residues), see Phobius details amino acids 321 to 346 (26 residues), see Phobius details amino acids 360 to 381 (22 residues), see Phobius details amino acids 387 to 405 (19 residues), see Phobius details PF07690: MFS_1" amino acids 26 to 374 (349 residues), 96.2 bits, see alignment E=9.7e-32

Best Hits

KEGG orthology group: None (inferred from 89% identity to vpe:Varpa_1234)

Predicted SEED Role

"major facilitator superfamily MFS_1"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (418 amino acids)

>GFF5327 Uncharacterized MFS-type transporter (Variovorax sp. SCN45)
VNPAVRPRVPVAAFAVLLGGVSGALHLGKLPPAVPALQASLGIGLVEAGFLLSLVQVASM
TLGLIAGLAADSIGLRRSMLTGLVILTVASLLGGWVGSGAVEGAHAVGWLLALRAVEGIG
FLLTVMPGPGLIRALTPPGADKAALGLWGAYMPLGVALALLVGPALIAWGGWPDWWWALS
VVSAVAALWLWLAVPADRLRPAAAGGASTAWSSRLRATVGARAPWLIALTFAVYSAQWMA
VIGFLPAIYAGAGVPAGWSAVLTALAAAMNIVGNIAGGRRLQRGVAPERLLQWGFLTMAL
GGVAAFAQAGQGADALGLPPVLRYVAVCAFSLGGGMVPATLFLLGVRFAPGPTTVSTTVG
LMQQASSLGQFLAPPAVAWVAHRVGGWHWTWTATLACSLVGMAIARRLGRIRPVAEMA