Protein Info for GFF5327 in Sphingobium sp. HT1-2

Annotation: Integron integrase IntI1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 337 TIGR02249: integron integrase" amino acids 16 to 330 (315 residues), 508.4 bits, see alignment E=4.1e-157 PF13495: Phage_int_SAM_4" amino acids 17 to 99 (83 residues), 95.7 bits, see alignment E=1.8e-31 PF00589: Phage_integrase" amino acids 116 to 316 (201 residues), 167.5 bits, see alignment E=2.5e-53

Best Hits

Swiss-Prot: 100% identical to INT2_PSEAI: Integrase/recombinase (int) from Pseudomonas aeruginosa

KEGG orthology group: None (inferred from 100% identity to eum:ECUMN_4814)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (337 amino acids)

>GFF5327 Integron integrase IntI1 (Sphingobium sp. HT1-2)
MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVHWVRAFIRFHGVRHPATLGSSE
VEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEIGRPRPSRRLPVVLTPD
EVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALML
PESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPRAGHSWPWFWVFAQHTHST
DPRSGVVRRHHMYDQTFQRAFKRAVEQAGITKPATPHTLRHSFATALLRSGYDIRTVQDL
LGHSDVSTTMIYTHVLKVGGAGVRSPLDALPPLTSER