Protein Info for PS417_27225 in Pseudomonas simiae WCS417

Annotation: protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 306 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF01145: Band_7" amino acids 23 to 193 (171 residues), 132.7 bits, see alignment E=2.4e-42 PF13421: Band_7_1" amino acids 86 to 176 (91 residues), 26.6 bits, see alignment E=6.5e-10 PF16200: Band_7_C" amino acids 240 to 299 (60 residues), 30.2 bits, see alignment E=5.7e-11

Best Hits

Swiss-Prot: 69% identical to QMCA_SHIFL: Protein QmcA (qmcA) from Shigella flexneri

KEGG orthology group: None (inferred from 100% identity to pfs:PFLU5868)

Predicted SEED Role

"Putative stomatin/prohibitin-family membrane protease subunit YbbK" in subsystem YbbK

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UJB7 at UniProt or InterPro

Protein Sequence (306 amino acids)

>PS417_27225 protease (Pseudomonas simiae WCS417)
MQIGTVLLLFVGLAIAILFMGFKVVPQGYQWTVERFGRYTNTLKPGLNIIIPVMDRIGRK
INVMESVLDIPPQEVITADNATVQIDAVCFFQVVNTAQAAYEVNNLEHAIRNLLQTNIRT
VLGSMELDAMLSQRDGINEKLLKTVDEATAPWGIKITRIEIKDISPPADLMAAMSGQMKA
ERIKRAQILEAEGLRASAILTAEGKKQAQILEAEGSRQAAFLESEARERQAEAEARATQV
VSEAIASGNVQAVNYFVAQKYIDALGKLASANNSKVILMPLEASQVIGAVGGIGEIVKAT
FDNKKG