Protein Info for PS417_27190 in Pseudomonas simiae WCS417

Annotation: taurine ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 328 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF13379: NMT1_2" amino acids 26 to 234 (209 residues), 45.4 bits, see alignment E=1.9e-15 PF04069: OpuAC" amino acids 27 to 235 (209 residues), 73.4 bits, see alignment E=4.8e-24 TIGR01729: taurine ABC transporter, periplasmic binding protein" amino acids 29 to 326 (298 residues), 431 bits, see alignment E=1.3e-133 PF12974: Phosphonate-bd" amino acids 49 to 220 (172 residues), 39.6 bits, see alignment E=8e-14 PF09084: NMT1" amino acids 66 to 243 (178 residues), 75.5 bits, see alignment E=1.2e-24

Best Hits

Swiss-Prot: 53% identical to TAUA_ECOLI: Taurine-binding periplasmic protein (tauA) from Escherichia coli (strain K12)

KEGG orthology group: K02051, sulfonate/nitrate/taurine transport system substrate-binding protein (inferred from 86% identity to pfo:Pfl01_5418)

MetaCyc: 53% identical to taurine ABC transporter periplasmic binding protein (Escherichia coli K-12 substr. MG1655)
ABC-64-RXN [EC: 7.6.2.7]

Predicted SEED Role

"Taurine-binding periplasmic protein TauA" in subsystem Taurine Utilization

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UGX7 at UniProt or InterPro

Protein Sequence (328 amino acids)

>PS417_27190 taurine ABC transporter substrate-binding protein (Pseudomonas simiae WCS417)
MAKRTSSRQFVTVFVSLILSFGVKAADLTIGYQTGIDPSKVPQADGLYEKAIGEKIAWRR
FNSGPEVVTAIASGDVQIGNLGSSPLAAAASRNLPIVAFIVSAQINTSEALVVRNGSHID
APKDLIGKTIATPFVSTSHYSLLGALKHWGLDTRQVKVVNLQPAEIAAAWKRGDIDGAFV
WSPALGEIRKTGKTLTDAAQVGQWGAPTFEVWVARKDFAEKHPDIVAKFAKVTLDSFAEY
AAHKDGWTVDSEPVQKIAKLTGSNAVDIPELLAGTTFPDAQAQQTDALLKGGTATAIGET
AKFLKEQGKVETVLPDYSAFVTDTFISK