Protein Info for GFF5296 in Variovorax sp. SCN45

Annotation: putative iron-regulated membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 390 transmembrane" amino acids 12 to 36 (25 residues), see Phobius details amino acids 146 to 169 (24 residues), see Phobius details amino acids 190 to 212 (23 residues), see Phobius details amino acids 339 to 360 (22 residues), see Phobius details PF03929: PepSY_TM" amino acids 10 to 362 (353 residues), 223.9 bits, see alignment E=6.4e-70 PF03413: PepSY" amino acids 59 to 120 (62 residues), 29.7 bits, see alignment E=9.6e-11

Best Hits

KEGG orthology group: None (inferred from 86% identity to vpe:Varpa_1209)

Predicted SEED Role

"putative iron-regulated membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (390 amino acids)

>GFF5296 putative iron-regulated membrane protein (Variovorax sp. SCN45)
MNSRTIKTWAWVHKWSSLVCTVFMLLLCITGLPLIFHHEIGHLLGTEVEAPKMPADTPRI
SLDRVLEIAKSRHPDRVVQFASRPEDDDGLWFVTLTPTPAPTDDFKSVAVDARTGDVLAQ
PKFDEGFMYVMFKLHVDLFAGLPGKLFLGFMGLLLLVAIVSGVVLYSPFMRKLDFGTVRR
DKRPRLKWLDLHNLLGVVTLVWLFVVGSTGMINTWADLLIKYWQYDQLSTLLAPYKNEPV
VAVSERGSMQRSMEAALQRAPGMKLSFIAFPGTSFSSPHHNTFFMRGSEPFSSKLFQPVL
VDAKTAEVTAAPRLPWYLTALLVSQPLHFGDYGGMPMQILWALLDIATIIVLGSGLYLWL
KRSNAPAKAAAQQQQQPQQPDPAPAMKAQA