Protein Info for GFF527 in Xanthobacter sp. DMC5

Annotation: Phosphatidate cytidylyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01148: CTP_transf_1
  • amino acids 9 to 254 (246 residues), 188.3 bits, E=1.3e-59

Best Hits

KEGG orthology group: K00981, phosphatidate cytidylyltransferase [EC: 2.7.7.41] (inferred from 77% identity to xau:Xaut_4434)

Predicted SEED Role

"Phosphatidate cytidylyltransferase (EC 2.7.7.41)" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria (EC 2.7.7.41)

MetaCyc Pathways

• phosphatidylglycerol biosynthesis I (6/6 steps found)
• phosphatidylglycerol biosynthesis II (6/6 steps found)
• superpathway of phospholipid biosynthesis III (E. coli) (10/12 steps found)
• CDP-diacylglycerol biosynthesis I (4/4 steps found)
• CDP-diacylglycerol biosynthesis II (4/4 steps found)
• superpathway of cardiolipin biosynthesis (bacteria) (10/13 steps found)
• CDP-diacylglycerol biosynthesis III (4/5 steps found)
• superpathway of phospholipid biosynthesis II (plants) (12/28 steps found)
• type I lipoteichoic acid biosynthesis (S. aureus) (4/17 steps found)

KEGG Metabolic Maps

• Glycerophospholipid metabolism
• Phosphatidylinositol signaling system

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.41

Protein Sequence (270 amino acids)

>GFF527 Phosphatidate cytidylyltransferase (Xanthobacter sp. DMC5)
VHFGSDLGHRTLSALVLVPLVLATAWYGGIPFAILWVAAGLLVLNEWAVIARLDHRPVYL
GLGGLGIVAGGVLAVTSDPTWAFSPVVLGAAACSLAVPRQSAWAMAGVLVAASAALPVVV
LRGSSALGLSAVLYLCAVVWATDIFAYFTGRALGGPKLWPRVSPNKTWSGAIGGTLLGTL
CGLAVAYASGAPALLPLAGLSLLLSIVSQAGDLAESAFKRLFGVKDASRLIPGHGGLLDR
LDGFAAAALVAVVVAVLRNAGDPATGLLLW