Protein Info for GFF5262 in Sphingobium sp. HT1-2

Annotation: Uncharacterized protein conserved in bacteria, NMA0228-like

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 276 PF05114: MbnB_TglH_ChrH" amino acids 8 to 267 (260 residues), 362.3 bits, see alignment E=7e-113

Best Hits

Swiss-Prot: 71% identical to Y4400_SPHWW: UPF0276 protein Swit_4400 (Swit_4400) from Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)

KEGG orthology group: K09930, hypothetical protein (inferred from 71% identity to swi:Swit_4400)

Predicted SEED Role

"Uncharacterized protein conserved in bacteria, NMA0228-like"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (276 amino acids)

>GFF5262 Uncharacterized protein conserved in bacteria, NMA0228-like (Sphingobium sp. HT1-2)
MIPSFPGFGLGLRKQHYADFLDDRIDVDFLEVISENFMIDGGRPRRILRDIRARYPVALH
GVSMSIGSADGLDGTYLARLRALVDDIEPLFVSDHLSWSRIEGFSSHDLLPLPYTQEALD
IVSANIDRAQNALGRAMLIENPSTYIDFAPADMTEWQFLDALCARTGCGLLLDVNNVFVS
ASNHGFDPIAYLDAVPHDRVRQIHLAGHSQGERLLIDTHDQPVPLSVWHLYAHVLPKLGP
VATMIERDDAIPPLADLMAELAIARGIAAGGMEKAA