Protein Info for GFF5236 in Variovorax sp. SCN45

Annotation: General secretion pathway protein N

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 266 transmembrane" amino acids 18 to 40 (23 residues), see Phobius details amino acids 61 to 82 (22 residues), see Phobius details PF01203: T2SSN" amino acids 52 to 260 (209 residues), 94.3 bits, see alignment E=5.9e-31

Best Hits

KEGG orthology group: K02463, general secretion pathway protein N (inferred from 82% identity to vpe:Varpa_1157)

Predicted SEED Role

"General secretion pathway protein N"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (266 amino acids)

>GFF5236 General secretion pathway protein N (Variovorax sp. SCN45)
MVTRPPSSGPAPRRGWRWALLGITIGAVLAVLLFAPARWLSAALSGWSQGRLVLANPRGT
IWNGTAAVVFASGAGGAEAVSLPGLLHWRMRPGWGGISASLDLPCCAAQPLQLRASPRAG
GMQLEWQDSRSRWPASMLTGLGAPWNTLKLDGALDLTTKAFAMQWDGPALRIAGQASLDA
TDVSSSLSTLRPMGSYRLTLEGGNRPTLLLSTREGSLELNGSGSWNGTTFRFNGEANAAP
GREDALSNLLNIIGRRDNARSIITLG