Protein Info for GFF5230 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: TRAP-type C4-dicarboxylate transport system, large permease component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 427 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 52 to 70 (19 residues), see Phobius details amino acids 78 to 101 (24 residues), see Phobius details amino acids 104 to 127 (24 residues), see Phobius details amino acids 139 to 163 (25 residues), see Phobius details amino acids 170 to 191 (22 residues), see Phobius details amino acids 211 to 234 (24 residues), see Phobius details amino acids 240 to 256 (17 residues), see Phobius details amino acids 271 to 294 (24 residues), see Phobius details amino acids 313 to 343 (31 residues), see Phobius details amino acids 354 to 375 (22 residues), see Phobius details amino acids 396 to 421 (26 residues), see Phobius details PF06808: DctM" amino acids 7 to 415 (409 residues), 415.8 bits, see alignment E=1.9e-128 TIGR00786: TRAP transporter, DctM subunit" amino acids 17 to 418 (402 residues), 494.2 bits, see alignment E=1.3e-152

Best Hits

Swiss-Prot: 58% identical to YIAN_ECOLI: 2,3-diketo-L-gulonate TRAP transporter large permease protein YiaN (yiaN) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 80% identity to aav:Aave_0751)

MetaCyc: 58% identical to 2,3-diketo-L-gulonate:Na+ symporter - membrane subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-235

Predicted SEED Role

"TRAP-type C4-dicarboxylate transport system, large permease component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (427 amino acids)

>GFF5230 TRAP-type C4-dicarboxylate transport system, large permease component (Hydrogenophaga sp. GW460-11-11-14-LB1)
MTIAIFLGTLLAAMAIGVPISFALLLSGVGLMWHMGMFDAQILAQNLTEGANSFPLLAVP
FFMLAGEIMNTGGLSRRIVNFAMALVGHVRGGLGYVTIVAACLLSALSGSAVADAAALTA
LLLPMMVKAGHDKARSGGLIAACGVIGPIIPPSIGFVIFGVAANVSISKLFLAGIFPGIL
LAAGLWATWWWTTRREKLEPPPRKSAREVIAAMRSAGWALMLPLIILVGLRMGVFTPTEA
AVVAAVYALFVAGVIYRELTVKQLYEVFLNAAKTTAVIMFLVAAAMVSAWLITVAQLPDQ
IVALLQPLLDSPMLLMFAIMLLVIAVGTAMDMTPTILILTPVLMPLVKAAGIDPVYFGVL
FIINNSIGLVTPPVGTVLNTVAGVGRMRMDDVTRGVMPFMLVQFAVMFLLVLFPSLVMVP
ARWLIGN