Protein Info for GFF520 in Variovorax sp. SCN45

Annotation: Efflux transport system, outer membrane factor (OMF) lipoprotein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 508 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details TIGR01845: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family" amino acids 17 to 480 (464 residues), 318.5 bits, see alignment E=3.8e-99 PF02321: OEP" amino acids 66 to 267 (202 residues), 52.6 bits, see alignment E=2.6e-18 amino acids 296 to 478 (183 residues), 102.1 bits, see alignment E=1.7e-33

Best Hits

KEGG orthology group: None (inferred from 83% identity to vap:Vapar_2412)

Predicted SEED Role

"RND efflux system, outer membrane lipoprotein, NodT family" in subsystem Multidrug Resistance Efflux Pumps

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (508 amino acids)

>GFF520 Efflux transport system, outer membrane factor (OMF) lipoprotein (Variovorax sp. SCN45)
MRRLRLFAALCLPLGFGLGLSGCALNRPPAQVEAPTPAQWHAPLPHGGSLASLADWWRQL
DDPLLVELIAAAEAASPNVASAAARVAEARFTRVQTGAALLPSLDGTASASRGTAGIASG
APSGGSASSSSSSSLGATTPITTLQVGLQSKWEVDLFGRLRADRDAAQAKLGSADAKWHD
ARVSVAAETANAYFAERACQQQLRVAESDTRSRAETSRLNDLSMRAGFTAPADAALARAS
AADASGRLTQQRAQCAVQRKALVALSGIDESTLEQKLAASPAQRALPAVGSIASVPAEAI
SQRPDVYSAELGVASASADVGSAEAERYPKLTISGSIGRTQYRVSGLQQSLENWTIGPVS
LSVPLLDGGSRKANADAAKARYAEAVSIYRANVRQAVREVEEALVNLDATDGRANDADTA
VKNYQASFDATQARYSSGLASLFELEDSRRTLFAAQTARVSLQRERTEAWVALYRSMGGG
WSRPGQPSESSESSSMNTTPAAKVATSP