Protein Info for GFF5195 in Variovorax sp. SCN45

Annotation: L-arabinose ABC transporter, ATP-binding protein AraG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 523 PF00005: ABC_tran" amino acids 29 to 180 (152 residues), 99 bits, see alignment E=3.6e-32 amino acids 289 to 444 (156 residues), 66.2 bits, see alignment E=4.7e-22

Best Hits

Swiss-Prot: 66% identical to ARAG_GEOSE: L-arabinose transport ATP-binding protein AraG (araG) from Geobacillus stearothermophilus

KEGG orthology group: K10548, putative multiple sugar transport system ATP-binding protein (inferred from 93% identity to vap:Vapar_1046)

Predicted SEED Role

"L-arabinose transport ATP-binding protein AraG (TC 3.A.1.2.2)" in subsystem L-Arabinose utilization (TC 3.A.1.2.2)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (523 amino acids)

>GFF5195 L-arabinose ABC transporter, ATP-binding protein AraG (Variovorax sp. SCN45)
VSTEGSLADAGVILEMRGITKTFPGVKALSNVNLGVRAGEIHAVVGENGAGKSTLMKVLS
GVYPCDSYEGEIRFEGEVRRFRGIADSEKLGIIIIHQELALVPLLSIAENIFLGNEITRG
GVIDWFAAYARTRELLAKVGLKEPPTTLVTDLGVGKQQLVEIAKALAKEVKLLILDEPTA
SLNEKDSDALLMLLLELKRQGIASILISHKLNEIAKVADSVTVLRDGATVETMDCRAQPI
SEDRIIRGMVGRDMAHRYPQRAPKIGETVFEVRDWRVHHALHADREQIKGVSLNVRQGEI
VGIAGLMGAGRTELAMSVFGRSYGQRISGSVLMHGKPVDVSTVRKAIDHGIAYVTEDRKG
LGLVLEEDIRRNISLANLEAVSESAVIDTGREFKVANEYRKALNIRCSGVEQLVVNLSGG
NQQKVVLSKWLFTKPELLILDEPTRGIDVGAKYEIYTIIDQLASEGKGILMISSELPELL
GMCDRIYVMNEGRFVAEFPVAEASQERIMHAIVSSGSSVHVPA