Protein Info for GFF5193 in Variovorax sp. SCN45

Annotation: Galactofuranose ABC transporter, substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF13407: Peripla_BP_4
  • amino acids 38 to 294 (257 residues), 166.1 bits, E=1.7e-52
• PF00532: Peripla_BP_1
  • amino acids 49 to 259 (211 residues), 54.1 bits, E=2.5e-18

Best Hits

Swiss-Prot: 54% identical to YTFQ_ECOLI: ABC transporter periplasmic-binding protein YtfQ (ytfQ) from Escherichia coli (strain K12)

KEGG orthology group: K02058, simple sugar transport system substrate-binding protein (inferred from 96% identity to vpe:Varpa_1113)

MetaCyc: 54% identical to galactofuranose ABC transporter periplasmic binding protein (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-491 [EC: 7.5.2.9]; 7.5.2.9 [EC: 7.5.2.9]

Predicted SEED Role

"Putative sugar ABC transport system, periplasmic binding protein YtfQ precursor"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.5.2.9

Protein Sequence (321 amino acids)

>GFF5193 Galactofuranose ABC transporter, substrate-binding protein (Variovorax sp. SCN45)
MTMNRRTLNTALAAAALGSMLPVSVFAQKKLVLGFAQVGAESEWRTANTESIKSSAKDAG
IELKFSDAQQKQENQIKAIRSYIAQKVDVIAFSPVVESGWETVLREAKAAKIPVVLTDRS
VSTKDDSLYVTFMGSDFIEEGRKAGRWLVEKMKDQKGDVNIVELQGTVGSAPAIDRKKGF
EEIIKADPKFKIIRSQTGDFTRAKGKEVMEAFLKADGKKINVLFAHNDDMAIGAIQAIEE
AGLKPAKDIVIISIDGVKGAFEAMIAGKLNVSVECSPLLGPQLMQAVKDIKDGKTLPKRI
VTVESIFPMEVAAKEFPNRKY