Protein Info for GFF5179 in Variovorax sp. SCN45

Annotation: Acetyltransferase, GNAT family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 187 PF13527: Acetyltransf_9" amino acids 48 to 158 (111 residues), 28.3 bits, see alignment E=3.8e-10 PF13673: Acetyltransf_10" amino acids 69 to 162 (94 residues), 44.3 bits, see alignment E=4.2e-15 PF00583: Acetyltransf_1" amino acids 71 to 157 (87 residues), 51.7 bits, see alignment E=2.6e-17 PF13508: Acetyltransf_7" amino acids 75 to 158 (84 residues), 49.3 bits, see alignment E=1.3e-16 PF08445: FR47" amino acids 99 to 158 (60 residues), 27.1 bits, see alignment E=8.7e-10

Best Hits

Swiss-Prot: 37% identical to TTR_PSEAJ: Acetyltransferase (ttr) from Pseudomonas amygdali pv. tabaci

KEGG orthology group: None (inferred from 77% identity to vpe:Varpa_1103)

MetaCyc: 37% identical to tabtoxinine-beta-lactam acetyltransferase (Pseudomonas syringae)
2.3.1.-

Predicted SEED Role

"GCN5-related N-acetyltransferase"

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (187 amino acids)

>GFF5179 Acetyltransferase, GNAT family (Variovorax sp. SCN45)
MTTTTNTTNTTPTTETPRIRALDTVTDAQVAALADLLIDCVDGGASVSFMHPLTAERAQA
FWRNVAAGVAAGERVLLVAEDAEGIVGTVQVVLAQPENQPHRGEVSKMLVHRRARRRGIG
ELLMRAAERQARERGKTLLVLDTSSPEAERLYARTGWTRVGSVPGFALLPQGEPCATTFF
YLELAGA