Protein Info for GFF5126 in Sphingobium sp. HT1-2

Annotation: L-sorbosone dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 431 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF22807: TrAA12" amino acids 59 to 276 (218 residues), 47.9 bits, see alignment E=1.2e-16 amino acids 320 to 426 (107 residues), 41.3 bits, see alignment E=1.3e-14 PF07995: GSDH" amino acids 192 to 355 (164 residues), 36.5 bits, see alignment E=5.4e-13

Best Hits

Swiss-Prot: 54% identical to SNDH_GLULI: L-sorbosone dehydrogenase from Gluconacetobacter liquefaciens

KEGG orthology group: None (inferred from 68% identity to bsb:Bresu_2073)

Predicted SEED Role

"L-sorbosone dehydrogenase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (431 amino acids)

>GFF5126 L-sorbosone dehydrogenase (Sphingobium sp. HT1-2)
MTVRAFILSAGLLALAACGRSQPGLDQTGDRPDLPDQRQTLLPPMKIATPAGWGNEKPTA
PAGFTVTAFATGLAIPRQMLVLPNGDILVAEGSGGSAPALRPKDVIATQIKAMGKTSVKG
GNRITLLRDADGDGRAELRSALITGLNAPYGLALVEGQLYVATQDALLRFPYREGETRIT
TPGVEVTRLPSRINHHWTKSLAAGPDGSKLYVGIGSNSNVGERGMAVEEDRAVIWEVDRQ
SGMHRTYASGIRNPTALAVEPQTRRLWAVVNERDELGPQLVPDYMTAVRPGAFYGWPYSY
WGQNVDPRVRPQQPDMVRRAIRPDYALGSHVAALGISFATGAGLGPAYAQGAFVGQHGSW
NRQDLAGYKVVFIPFANGRPAGKPQDFLTGFIKDGHARGRPVGVSYDPVHGALLVADDLS
NSVWRIAPTRR