Protein Info for PS417_26070 in Pseudomonas simiae WCS417

Annotation: amino acid ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 331 transmembrane" amino acids 86 to 104 (19 residues), see Phobius details PF16220: DUF4880" amino acids 15 to 54 (40 residues), 48.3 bits, see alignment 7.3e-17 PF04773: FecR" amino acids 117 to 207 (91 residues), 80.5 bits, see alignment E=1e-26

Best Hits

KEGG orthology group: None (inferred from 95% identity to pfs:PFLU5628)

Predicted SEED Role

"Transmembrane sensor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UA56 at UniProt or InterPro

Protein Sequence (331 amino acids)

>PS417_26070 amino acid ABC transporter substrate-binding protein (Pseudomonas simiae WCS417)
MTVISSRPVSARVLDAAIAWQLSLDSGDGSAIEREEFDKWLASDEEHARAWRQLGMLDQR
FSVASGPARAALLQSREGIRQRVRKLGSGLASVALVIGLALFAGERYVPIHYWLADQRTA
TGEQRTLKLSDGTLINLNTHSAIDVRFDEKRRLVVLQEGEILVETGHNDERPFYVQTRDG
SLRALGTRFIVKREDDATRLSVLQSAVAAQPEALHQEQVFKEGQQVLMRSDGLGPLLAVT
PATDAWTRGMLVVDNARLGEVVEELSRYRTGYLGVDKNVADLRITGSFPLHDTTLALNAL
LPTLPVHIEQHTPWWVTVKATAKNTESLSEK