Protein Info for GFF508 in Sphingobium sp. HT1-2

Annotation: Nucleoside permease NupC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 437 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details transmembrane" amino acids 29 to 50 (22 residues), see Phobius details amino acids 63 to 80 (18 residues), see Phobius details amino acids 88 to 113 (26 residues), see Phobius details amino acids 166 to 188 (23 residues), see Phobius details amino acids 193 to 214 (22 residues), see Phobius details amino acids 283 to 312 (30 residues), see Phobius details amino acids 318 to 338 (21 residues), see Phobius details amino acids 345 to 361 (17 residues), see Phobius details amino acids 374 to 397 (24 residues), see Phobius details amino acids 414 to 435 (22 residues), see Phobius details PF01773: Nucleos_tra2_N" amino acids 8 to 81 (74 residues), 87.4 bits, see alignment E=1.2e-28 PF07670: Gate" amino acids 93 to 190 (98 residues), 50.8 bits, see alignment E=3.1e-17 PF07662: Nucleos_tra2_C" amino acids 195 to 432 (238 residues), 254.7 bits, see alignment E=1.1e-79

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (437 amino acids)

>GFF508 Nucleoside permease NupC (Sphingobium sp. HT1-2)
MHLLIGLAGILLILAIAFALSSNRRAIRLRVVGAAFLLQAGIALLVLYVPAGRAIIAGMS
HGVANLLGYAQAGTNFIFGPLAKPEIGGASFAIAALPVIIFFASLVSILYYLGIMQFIVR
WVGGAIEKVTGVSKVESLCAAANIFVGQSESPLVIRPYLAGLNGPQLFAVMTSGMAGVAG
TILAAYASMGIKIDYLLAASFMAAPGGLLMAKIMMPDEPECEPELPLEDDIHLPETRRAA
AVAAVLNAETTPGEPMPVATHDEEKPANIIMAAAQGAQTGVKLAVAVGAMVLAFVALVAL
ANGILGGIGGIFGYPELSFQQLLGYVFSPVMYLLNIPWNEAQVAGGLFGTKVVLNEFVAY
INLGQVQDGLSPSTIAIITFALCGFANFSSIAIQMAVTGNLAPNQRPMIAKLGLKALVAG
SLANLMSAALAGLMLSL