Protein Info for PS417_25910 in Pseudomonas simiae WCS417

Annotation: amine oxidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 560 PF13450: NAD_binding_8" amino acids 50 to 117 (68 residues), 36.3 bits, see alignment E=5.7e-13 PF01593: Amino_oxidase" amino acids 55 to 530 (476 residues), 153.9 bits, see alignment E=8.8e-49

Best Hits

KEGG orthology group: K00466, tryptophan 2-monooxygenase [EC: 1.13.12.3] (inferred from 99% identity to pfs:PFLU5595)

MetaCyc: 90% identical to L-lysine monooxygenase monomer (Pseudomonas putida)
Lysine 2-monooxygenase. [EC: 1.13.12.2]

Predicted SEED Role

"Lysine 2-monooxygenase (EC 1.13.12.2)" in subsystem Lysine degradation (EC 1.13.12.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.13.12.2 or 1.13.12.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UIL6 at UniProt or InterPro

Protein Sequence (560 amino acids)

>PS417_25910 amine oxidase (Pseudomonas simiae WCS417)
MSKTNRHPADGKKPITIFGPDFPFAFDDWIEHPAGLGSIPTANHGAEVAIVGAGIAGLVA
AYELMKLGLKPVVYEASKMGGRLRSQAFEGAEGIIAELGGMRFPVSSTAFYHYVDKLGLE
TKPFPNPLTPASGSTVIDLEGQTHYAQKLSDLPVLFQEVADAWADALEAGSQFGDIQQAI
RDRDVPRLKELWNKLVPLWDDRTFYDFVATSKAFAKLSFHHREVFGQVGFGTGGWDSDFP
NSMLEIFRVVMTNCDDHQHLVVGGVAQVPMGIWRHVPERCAHWPAGTSLSSLHRGAPRAG
VKRIAHAADGRFAVTDNYGDTREYAAVLTTCQSWLLTTQIECDETLFSQKMWMALDRTRY
MQSSKTFVMVDRPFWKDKDPETGRDLMSMTLTDRLTRGTYLFDNGDDKPGVICLSYSWMS
DALKMLPQPIDKRVKLALDALKKIYPKVDIKARIIGDPITVSWEADPHFLGAFKGALPGH
YRYNQRMYAHFMQKDMPAEQRGIFIAGDDVSWTPAWVEGAVQTSLNAVWGIMTHFGGSTH
PENPGPGDVFDEIGPIALAD