Protein Info for GFF5052 in Sphingobium sp. HT1-2

Annotation: Pirin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 298 PF02678: Pirin" amino acids 26 to 131 (106 residues), 120.1 bits, see alignment E=4.5e-39 PF05726: Pirin_C" amino acids 184 to 284 (101 residues), 101.2 bits, see alignment E=3.8e-33

Best Hits

Swiss-Prot: 52% identical to Y3178_CAUVC: Pirin-like protein CC_3178 (CC_3178) from Caulobacter vibrioides (strain ATCC 19089 / CB15)

KEGG orthology group: K06911, (no description) (inferred from 83% identity to npp:PP1Y_AT4463)

Predicted SEED Role

"Pirin-related protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (298 amino acids)

>GFF5052 Pirin (Sphingobium sp. HT1-2)
MSIRTSEVDGVDLVILPPVRDLGDGFSVRRALPSAHRRMVGPFIFFDQMGEAVFNSGEGL
DVRPHPHIGLATVTYLLEGEILHRDSVGSVQSIRPGEVNWMTAGSGIVHSERTSEENRAK
GGKLFGLQTWVALPTQAEEVDPGFAHHKADEIPTIEDAGTRLTLIAGSSDGLVSPVKTFS
DMVYADIVLQDGARYQLKAEHVERAIYVVQGEVEVIGQTGGFATGELVVFKPGAEIILRA
RGATRLMLMGGEPLPEKRHIFWNFVSSSPERIEQAKADWQAQRFAPVPEEHEFIPLPA