Protein Info for GFF502 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Type III secretion inner membrane protein (YscU,SpaS,EscU,HrcU,SsaU, homologous to flagellar export components)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 transmembrane" amino acids 32 to 56 (25 residues), see Phobius details amino acids 86 to 110 (25 residues), see Phobius details amino acids 139 to 157 (19 residues), see Phobius details amino acids 181 to 204 (24 residues), see Phobius details TIGR01404: type III secretion protein, YscU/HrpY family" amino acids 2 to 342 (341 residues), 334.2 bits, see alignment E=5e-104 PF01312: Bac_export_2" amino acids 2 to 339 (338 residues), 314.6 bits, see alignment E=4.5e-98

Best Hits

KEGG orthology group: K03229, type III secretion protein SctU (inferred from 41% identity to hch:HCH_03260)

Predicted SEED Role

"Type III secretion inner membrane protein (YscU,SpaS,EscU,HrcU,SsaU, homologous to flagellar export components)" in subsystem Type III secretion systems, extended

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (350 amino acids)

>GFF502 Type III secretion inner membrane protein (YscU,SpaS,EscU,HrcU,SsaU, homologous to flagellar export components) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MSEKTEKPTPKRLVDARKKGDVAHAKDASKALLIWACAGYLLFSAGQLTDAMLFLIEWAG
AHANGPFRDVLAAFLRLALKELGLALLPWMAIVIVLSIFGELVTAGPVFAPEKVKFNFQK
LDVVANVKNLFSARNLIEALKSVVKVLALTGIVWKLVHDNLGTLMLLAGSGIQPVTTGFG
LLIKSLLLATAFVFTVIAGFDMLIQRKLFSRQQMMTKDEVKRERKESDGAPEIKGERRKL
HREIVQGGGGGKRKPSLVVTNPTHLAVALLYEHGETPLPLVVAKGAGLQAQAIVRDARVD
GIPIIQHIPLARALVAQVEVDDPVPEHLFELVIDVLKAVKEVAPAERPRS