Protein Info for PS417_25655 in Pseudomonas simiae WCS417

Annotation: iron--sulfur cluster insertion protein ErpA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 116 PF01521: Fe-S_biosyn" amino acids 11 to 111 (101 residues), 69.5 bits, see alignment E=1.4e-23 TIGR00049: iron-sulfur cluster assembly accessory protein" amino acids 12 to 115 (104 residues), 127.5 bits, see alignment E=1.1e-41

Best Hits

Swiss-Prot: 100% identical to ERPA_PSEFS: Iron-sulfur cluster insertion protein ErpA (erpA) from Pseudomonas fluorescens (strain SBW25)

KEGG orthology group: None (inferred from 92% identity to ppu:PP_0433)

Predicted SEED Role

"probable iron binding protein from the HesB_IscA_SufA family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UIG4 at UniProt or InterPro

Protein Sequence (116 amino acids)

>PS417_25655 iron--sulfur cluster insertion protein ErpA (Pseudomonas simiae WCS417)
MSVESFTPTALQFTHGAAHKVKSLVDEEGNDRLKLRVFVTGGGCSGFQYGFTFDEDVADD
DTIVEREGVSLVVDPMSFQYLAGAEVDYQEGLEGSRFVIKNPNATTTCGCGSSFSI