Protein Info for GFF5000 in Variovorax sp. SCN45

Annotation: PUTATIVE ZINC PROTEASE PROTEIN

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 374 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF10023: Aminopep" amino acids 22 to 351 (330 residues), 420.7 bits, see alignment E=2.2e-130

Best Hits

KEGG orthology group: None (inferred from 86% identity to vpe:Varpa_0351)

Predicted SEED Role

"PUTATIVE ZINC PROTEASE PROTEIN"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (374 amino acids)

>GFF5000 PUTATIVE ZINC PROTEASE PROTEIN (Variovorax sp. SCN45)
VKLLSALALAGSVFLTGCADLGYYWQSASGHIGIMRAAKPVPEWLADPSVSAALKAKLEL
TQRIRRFASAELGLPDNPSYKSYADLHRAAAVWNVVAAPPYSLTLKSWCFPVAGCVGYRG
YYDEALAKAEAEAQKKEGMEVAVYPVPAYSTLGWMNWAGGDPLLSTFIGYPEGELARIVF
HELAHQVLYVPGDTVFNESYATAVERIGGALWLQREAGEPARREYAQFDMQRQDFRALAL
DTRRALTQVYESPEAKAKDWARVEVMKQAAMADFRERYAKLKAGWSGPRQNAYDAWVARA
NNAAFGAQGAYDDLVPSFEQLFEREGHEWPRFYTEVKRIAALPTEQERRAALASASGVLQ
THSSPKDNKENSGA