Protein Info for GFF5 in Xanthobacter sp. DMC5

Annotation: 50S ribosomal protein L1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 232 TIGR01169: ribosomal protein uL1" amino acids 3 to 227 (225 residues), 335.3 bits, see alignment E=7.5e-105 PF00687: Ribosomal_L1" amino acids 30 to 220 (191 residues), 232.8 bits, see alignment E=1.4e-73

Best Hits

Swiss-Prot: 96% identical to RL1_XANP2: 50S ribosomal protein L1 (rplA) from Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2)

KEGG orthology group: K02863, large subunit ribosomal protein L1 (inferred from 96% identity to xau:Xaut_3361)

MetaCyc: 56% identical to 50S ribosomal subunit protein L1 (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"LSU ribosomal protein L1p (L10Ae)" in subsystem Ribosome LSU bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (232 amino acids)

>GFF5 50S ribosomal protein L1 (Xanthobacter sp. DMC5)
MAKEGKRIRAVNEGIDRNKLYGLDDALKLLKERTTAKFDETIEVALNLGVDPRHADQMVR
GVCNLPNGSGRTVRVAVFARGAKADEAKAAGADIVGAEDLLETIQGGTIDFDRCIATPDL
MPLVGRLGKVLGPRGLMPNPKVGTVTMDVKGAVAAAKGGAVEFRVEKAGIIHGGIGKASF
PADKLAENIRAFVDAVVKAKPAGAKGTYLQRVAVSSTMGPGIKVEPSSVLTA