Protein Info for GFF4965 in Sphingobium sp. HT1-2

Annotation: putative membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 227 signal peptide" amino acids 18 to 19 (2 residues), see Phobius details transmembrane" amino acids 20 to 35 (16 residues), see Phobius details amino acids 42 to 58 (17 residues), see Phobius details amino acids 70 to 89 (20 residues), see Phobius details amino acids 117 to 134 (18 residues), see Phobius details amino acids 146 to 167 (22 residues), see Phobius details amino acids 194 to 209 (16 residues), see Phobius details PF09997: DUF2238" amino acids 49 to 196 (148 residues), 153.6 bits, see alignment E=1.6e-49

Best Hits

KEGG orthology group: K08984, putative membrane protein (inferred from 70% identity to sjp:SJA_C1-16890)

Predicted SEED Role

"conserved hypothetical protein-putative membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (227 amino acids)

>GFF4965 putative membrane protein (Sphingobium sp. HT1-2)
MISGAVAVWKSLPAAQRRMITTLLVAIGLANVAQPFPDLAPLQHGPTLLLTLAAPWLLKR
WPLSSRSVGCIWLFLLLHTFGARWIYSYVPYDDWARMLSGHDISSFLGLQRNAYDRLVHF
AFGALLTAPVAEIARRKGGLCHGWSLAFAFAAIGLGSALYEIFEWLLTVIAAGETADYYN
GQQGDVWDPQKDMAAAQIGSALALIALLRGRGGDPIGEAPSPEGPAQ