Protein Info for GFF4964 in Variovorax sp. SCN45

Annotation: Sulfate permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 487 transmembrane" amino acids 21 to 41 (21 residues), see Phobius details amino acids 47 to 63 (17 residues), see Phobius details amino acids 69 to 86 (18 residues), see Phobius details amino acids 92 to 113 (22 residues), see Phobius details amino acids 122 to 140 (19 residues), see Phobius details amino acids 144 to 164 (21 residues), see Phobius details amino acids 171 to 188 (18 residues), see Phobius details amino acids 220 to 243 (24 residues), see Phobius details amino acids 262 to 282 (21 residues), see Phobius details amino acids 295 to 315 (21 residues), see Phobius details amino acids 321 to 341 (21 residues), see Phobius details amino acids 353 to 383 (31 residues), see Phobius details PF00916: Sulfate_transp" amino acids 20 to 358 (339 residues), 156.6 bits, see alignment E=8e-50 PF01740: STAS" amino acids 403 to 479 (77 residues), 43.2 bits, see alignment E=3e-15

Best Hits

Swiss-Prot: 50% identical to YBAR_BACSU: Putative sulfate transporter YbaR (ybaR) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 93% identity to vpe:Varpa_0379)

Predicted SEED Role

"Sulfate permease" in subsystem Cysteine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (487 amino acids)

>GFF4964 Sulfate permease (Variovorax sp. SCN45)
MSSSPHSRLRAEWCPSIPRELMAGAVATFALIPEVIAFSFVAGVDPAVGLFASFVIGIVI
AFTGGRPAMVSAAAGSVALVAAPLVHAHGLPYLLAAGVLAGLMQIVFGLLRLGVLMRFVS
SSVRTGFVNALAILIFAAQMPHFIGANMATWAMVGLGLAVIYLLPRITTAVPSPLVCIVV
VTLVGHWLDLPLKTVADLGQLPGALPAFALPDVPLTLETLRIIALPAFAIAMVGLLESMM
TASVVDELTDTPSSKNRECSGLGVANVAASFFGGIAGCGMIGQTVSNVRYGGRGRLSTLF
AGAFLLILMVALKPWVSQVPVAALVAIMVMVSASTFDWGSLRALVRHPRMSSAVMLATVA
VTVATDNLAAGVATGVMLSGVFFTFKVARLLHVDAQPGEEGAARVYRVRGQVFFASADML
VDAFDVREIDGAPVRIDVSAAHFWDVTAVAALRKVVERLRKHGSTVEVTGMNQASRDLVL
QLDAAPE