Protein Info for PS417_02530 in Pseudomonas simiae WCS417

Annotation: iron ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 341 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details PF13531: SBP_bac_11" amino acids 46 to 291 (246 residues), 74.7 bits, see alignment E=1.9e-24 PF01547: SBP_bac_1" amino acids 50 to 287 (238 residues), 85.5 bits, see alignment E=1.4e-27 PF13416: SBP_bac_8" amino acids 51 to 305 (255 residues), 79.5 bits, see alignment E=7.7e-26 PF13343: SBP_bac_6" amino acids 86 to 304 (219 residues), 81.4 bits, see alignment E=1.5e-26

Best Hits

Swiss-Prot: 45% identical to FBPA_NEIMA: Major ferric iron-binding protein (fbpA) from Neisseria meningitidis serogroup A / serotype 4A (strain Z2491)

KEGG orthology group: K02012, iron(III) transport system substrate-binding protein (inferred from 99% identity to pfs:PFLU0528)

Predicted SEED Role

"Ferric iron ABC transporter, iron-binding protein" in subsystem Campylobacter Iron Metabolism or Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UF47 at UniProt or InterPro

Protein Sequence (341 amino acids)

>PS417_02530 iron ABC transporter substrate-binding protein (Pseudomonas simiae WCS417)
MTIRDTRLKTSLLRGLTLTLLGLTLLSPTAYSADKVSLTLYNGQHKEVGDELAKAFEAKT
GIHVNVRKGSSNQLASQVVEEGDRSPADVIYTEESPPLNKLGEQGLLAKIDASTLDVLPK
DYVGANGDWMGVTARTRVVAFNPKLIAEKDLPKSVLDFAGPEWQGKVGFVPTSGAFQEQA
VAIIKLHGREAAEEWLTGLRAFGKVYSNNMVALKAVENGEVATVLVNNYYWFALKKEKTN
LDSQLHYFTNGDAGGLITVSSAAALKSSKHPKEAQQLLAFMASEEGQRVITNTSAEYPLR
KGMESNRGLKPFSELQPPKVTPADLGNAEEALDLERDVGLN