Protein Info for GFF4959 in Sphingobium sp. HT1-2

Annotation: UPF0301 protein YqgE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 186 PF02622: DUF179" amino acids 16 to 173 (158 residues), 143.2 bits, see alignment E=3.5e-46

Best Hits

Swiss-Prot: 56% identical to Y683_NOVAD: UPF0301 protein Saro_0683 (Saro_0683) from Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CIP 105152 / NBRC 16084 / F199)

KEGG orthology group: K07735, putative transcriptional regulator (inferred from 77% identity to sch:Sphch_0735)

Predicted SEED Role

"UPF0301 protein YqgE"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (186 amino acids)

>GFF4959 UPF0301 protein YqgE (Sphingobium sp. HT1-2)
MTDPRFYGGRFLLALPGMEDERFDHSVIALCVHDEDGALGISLSEEVEGVGLRDLLQSFD
IDASAIPDQPVLKGGPVEPRRGFVLHSLDWVGQDMVQSGPDWGLSGSLDILKAIAEGRGP
SRYLVALGYAGWGAGQLEREMAGESWFLAEGDAALLFDTPAHRKWRAAYAAAGVDSAHLV
SGGGLA