Protein Info for GFF4933 in Variovorax sp. SCN45

Annotation: Dipeptide transport ATP-binding protein DppD (TC 3.A.1.5.2)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 282 PF00005: ABC_tran" amino acids 30 to 181 (152 residues), 82.1 bits, see alignment E=3e-27

Best Hits

Swiss-Prot: 38% identical to OPPD_HAEIN: Oligopeptide transport ATP-binding protein OppD (oppD) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K02031, peptide/nickel transport system ATP-binding protein (inferred from 59% identity to rsk:RSKD131_2167)

Predicted SEED Role

"Dipeptide transport ATP-binding protein DppD (TC 3.A.1.5.2)" in subsystem ABC transporter dipeptide (TC 3.A.1.5.2) (TC 3.A.1.5.2)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (282 amino acids)

>GFF4933 Dipeptide transport ATP-binding protein DppD (TC 3.A.1.5.2) (Variovorax sp. SCN45)
MAELLIEDLTVTYPTASGPVDVVKSLSLRMGAERIGIVGESGSGKSMTARAILGLVRSPG
RATASRMAYDGADLLRQTPSGWRAIRGRRIGMVLQDPKFSLNPVLRVGRQIAEAGLLHGV
FKPAQARDRVLEMLRTVGVDNPERVHDAYPHQLSGGIGQRVMIAAMMIAEPGLLIADEPT
SALDVMVRGQVLEMMDREIRKRGMGLLMISHDLKMVAHFCDRVLVMYRGQVVESCAAKDL
FRSQHPYTRGLLNCMPTGQNPGQPLPTIDRQLIQETVDRHAK