Protein Info for GFF4911 in Xanthobacter sp. DMC5

Annotation: Multicopper oxidase MmcO

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 518 signal peptide" amino acids 1 to 37 (37 residues), see Phobius details PF07732: Cu-oxidase_3" amino acids 55 to 138 (84 residues), 25.2 bits, see alignment E=2.3e-09 PF00394: Cu-oxidase" amino acids 264 to 352 (89 residues), 42.8 bits, see alignment E=9.3e-15 PF07731: Cu-oxidase_2" amino acids 410 to 517 (108 residues), 102.8 bits, see alignment E=2.1e-33

Best Hits

KEGG orthology group: None (inferred from 79% identity to xau:Xaut_3408)

Predicted SEED Role

"Multicopper oxidase" in subsystem Copper homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (518 amino acids)

>GFF4911 Multicopper oxidase MmcO (Xanthobacter sp. DMC5)
MTRPNHSSSLSRRTVLAGGAAAGALALSGGWSRVLAAPLITVESLTLDVNGKAAKVFAVK
GPAGEGLFAREGDRLTGTVLNASQTPAVMHWHGQVLAPADQDRARPDGGELAPGGTDQVD
FVLTPGTHWMHAHTLSEQQLLAAPLVTREADAGDVQDVVVMLHDFSFRSPEEILAGLGGA
GGHGGHAMEQPAQGAGMPGMAMPGMPMPATAMPGMSHAGHAMGGMPPASGAMGGGAMGGA
AMGPTGGGAPMAHANDVAYDAFLANRRTLADPQVVQVEKGGRVRLRIINGGTATAFFVAV
PGLKPRCIAVDGTPCVPVEAEAFPLAQGQRIDLLVAIPSGGGAFPVLAQVEASDRRTGLV
LATPGAAVARLAEAAAAPAGLLDLAFEGRLAAVRPLVVRKADRAFPVMLGEEAGYRWTIN
GRGAGEAEPFTVMQGERVEMSFMNPTTMSHPMHLHGHHFQVVALGGRRFSGALRDTVMVP
PHMPVTIAFDAGQKGEWFLHCHHLYHMAAGMMAVVKVA