Protein Info for GFF491 in Xanthobacter sp. DMC5

Annotation: Vitamin B12 import ATP-binding protein BtuD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 584 transmembrane" amino acids 7 to 24 (18 residues), see Phobius details amino acids 35 to 53 (19 residues), see Phobius details amino acids 61 to 80 (20 residues), see Phobius details amino acids 86 to 105 (20 residues), see Phobius details amino acids 110 to 131 (22 residues), see Phobius details amino acids 157 to 177 (21 residues), see Phobius details amino acids 203 to 224 (22 residues), see Phobius details amino acids 236 to 253 (18 residues), see Phobius details amino acids 260 to 277 (18 residues), see Phobius details amino acids 282 to 303 (22 residues), see Phobius details PF02653: BPD_transp_2" amino acids 35 to 292 (258 residues), 114.9 bits, see alignment E=7.4e-37 PF00005: ABC_tran" amino acids 350 to 508 (159 residues), 110.3 bits, see alignment E=2.3e-35 PF12399: BCA_ABC_TP_C" amino acids 558 to 580 (23 residues), 44.6 bits, see alignment (E = 1.7e-15)

Best Hits

Predicted SEED Role

"Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1)" in subsystem ABC transporter branched-chain amino acid (TC 3.A.1.4.1) (TC 3.A.1.4.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (584 amino acids)

>GFF491 Vitamin B12 import ATP-binding protein BtuD (Xanthobacter sp. DMC5)
MPRIPRLAAYALAIAVIAIFPLIAPNPFFVHVGQTFAYTAIAVIGLNILLGLSGQMSLGH
GGFYAVGAYVSAILATTYGWPLTLSMGVALAACLLAGLLVGAVALRTRGLYLAMATLAFG
FIVEIVAQRWVSVTGGTMGVMGVPQIDFGNFRMGPTYFFWVAAGILLLVQVGSDYVFGSS
IGRRLNAIKESESFAATVGLNVPLWRIGVFAASAALAGLAGVLFAHQSGFVSSDAFNIRL
TISLLIATVIGGLGRSAGPLLGTAILIGIAEAIAAVHDIGLMLYGGILLVVLLVFPEGAI
GLFGRRRATTAVAPEAAPAFHPAIAGRGRAGGRLDVESVTKSYAGVVALREATLSVEPGT
VHALIGPNGAGKSTFINVVAGLYAPTSGHIRIGGVDVTDLPAHRRARLGLVRTFQNLQLI
QGVSVLENVMLGMERRRGLAADVLAFLGGSGHEARERAEAASILAFLGIGHLADMKPKDL
SYGHRKLVELARAIAQKPAILLLDEPVAGVNPQEAREVARIVAKLRDAGISVLLVEHNME
FVMGLADRVTVLDFGNPIASGTPAEVQKDPKVIRAYLGAVEDAA