Protein Info for GFF4855 in Sphingobium sp. HT1-2

Annotation: DNA polymerase IV-like protein ImuB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 467 PF00817: IMS" amino acids 3 to 107 (105 residues), 38.9 bits, see alignment E=8.2e-14 PF20114: DUF6504" amino acids 385 to 462 (78 residues), 29.3 bits, see alignment E=8.4e-11

Best Hits

KEGG orthology group: K14161, protein ImuB (inferred from 83% identity to swi:Swit_4948)

Predicted SEED Role

"DNA polymerase-like protein PA0670" in subsystem DNA repair, bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (467 amino acids)

>GFF4855 DNA polymerase IV-like protein ImuB (Sphingobium sp. HT1-2)
VDAAARALGVMPGMTVTKARMLAPELEVIDALPDADMDGLRRLALWAGQRYSPIVAPDAP
DGLWIDITGCASLFGSETALLKDLHRRIAAFGVAVHIAVADTAGCAHAVARHVRDGRPVV
IEPGQHRRAMELLPIPALRLEAEIVEGLRKLGFERVEQLLGAPRAPLAKRFGRSLHRRLD
QAIGQVAEPIEPIFPEQMPRAQRGFMEPIATPEAFAQVIGDLVADIVEQLARAGRGGRRL
DCYFHRVDGHCQVIRIGTATPSRDAGHLAKLLCAKIETVEPGLGIEAMTLLVSLMEAAAP
RQGESLEQLGRRGPDLAALVDTLANRFGSRNLHRMAPCPSGMPERSATGAPALGEARGMG
WDDDLPRPARMLAKPEPIEVIALLPDDAPRMFIWRGKRYRVTQGDGPERLHGEWWRDGGI
EGRQPLSVRDYYQVETVSGGRYWLFRAGDGESAATGPMRWFIHGAFA