Protein Info for GFF4830 in Variovorax sp. SCN45

Annotation: Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 320 PF01965: DJ-1_PfpI" amino acids 2 to 182 (181 residues), 44.1 bits, see alignment E=3.1e-15 PF12833: HTH_18" amino acids 241 to 317 (77 residues), 61.6 bits, see alignment E=1.1e-20

Best Hits

KEGG orthology group: None (inferred from 73% identity to axy:AXYL_03738)

Predicted SEED Role

"Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (320 amino acids)

>GFF4830 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain (Variovorax sp. SCN45)
MKIDVLALDGVFDTGLSTVLDVFTTANELAAMLQLDVAPFEVVVAGMRKRVRTAQGFAVP
VARTLEAGAADWLIVPALGCKMPETLEPALQRADVRDACSALRERTSKGAHIAAACIGTF
VLAEAGVLDHQKATTTWWLATLFRQRYPAVQLEDSRMLVSSSHLVTAGAALSHVDMALWI
VRQASPELATLVARYLIVDSRPSQSAYVISDHLSHSDPLVERFERWARGRLALGFSLDEA
AQAAGTSKRTLARRMQQVLGKSPLSYVQDLRVERAVHLLKTSDKSLEQIAGMVGYADGVT
LRTLLRQRLGRGVREVRLEA