Protein Info for PS417_24685 in Pseudomonas simiae WCS417

Annotation: peptidase S66

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 306 PF02016: Peptidase_S66" amino acids 14 to 129 (116 residues), 135.6 bits, see alignment E=9.7e-44 PF17676: Peptidase_S66C" amino acids 180 to 289 (110 residues), 118.3 bits, see alignment E=3.1e-38

Best Hits

KEGG orthology group: K01297, muramoyltetrapeptide carboxypeptidase [EC: 3.4.17.13] (inferred from 92% identity to pfs:PFLU5415)

Predicted SEED Role

"Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13)" (EC 3.4.17.13)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.17.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UFJ8 at UniProt or InterPro

Protein Sequence (306 amino acids)

>PS417_24685 peptidase S66 (Pseudomonas simiae WCS417)
MTAAVPALRSEGTIALIAPAGPAILDVEKAGQWMRTRGYDLRIFPGVYERDGYLAGSDKT
RLNDLHNAFANPDIDAIFCLRGGYGTPRLLDSLDFDLLRANPKPFVGYSDITALHLAISR
YAGFVTFHGPMLNADLLGDKQQPTESSLFSMLRGQLGAGSVLAHPAAYPLTTLEPGIACG
RLLGGNLSMIAAVMGTPFEIDAEGIILLIEDVNEPIYRIDRLLTHLRLAGKLAQVAGVLV
GDVAGVDSAALERLLKQTFEPLRIPVLSGWRSGHCDPNLTLPMGALVRLDAGEKRVVLEQ
DVVFKA