Protein Info for PS417_24680 in Pseudomonas simiae WCS417

Annotation: murein transglycosylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 441 signal peptide" amino acids 1 to 36 (36 residues), see Phobius details TIGR02283: lytic murein transglycosylase" amino acids 68 to 366 (299 residues), 387 bits, see alignment E=2.9e-120 PF13406: SLT_2" amino acids 68 to 362 (295 residues), 377.4 bits, see alignment E=4.6e-117 PF01471: PG_binding_1" amino acids 383 to 438 (56 residues), 50.3 bits, see alignment 2.2e-17

Best Hits

KEGG orthology group: None (inferred from 98% identity to pfs:PFLU5414)

Predicted SEED Role

"Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-)" in subsystem Peptidoglycan Biosynthesis (EC 3.2.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.-

Use Curated BLAST to search for 3.2.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UP09 at UniProt or InterPro

Protein Sequence (441 amino acids)

>PS417_24680 murein transglycosylase (Pseudomonas simiae WCS417)
MPSSLSHRWHLRQLIAASSLILLVACAEKPTAADAQPLPKLQTAPVVAPAVVAPLAVDNL
DIQPTQTFAEWQAGFRVQALQAGITAAVFDNAFANVTPDMAVIRADRSQPEFSRPVWEYL
DGALSPLRVRNGQSLLIKYADILQSIEQRYGVDRQALVSVWGMESNFGQFQGNNSVIRSL
ATLAYEGRRPAFAQAQLLAALQIIQHGDIQADQMKGSWAGAMGQTQFIPTTYNTHAVDFD
GDGRRDIWNSPADALASTAHYLQSSGWQKGQPWGFEVKQLPANFDYALADGGIRKTVAEW
LKLGIQLPPGATLPPNVDQLSAALLLPAGYRGPAFLVLDNFRAILKYNNSSSYALAVGLL
SERFAGGGVIRGDWPKDELPLSRSQRIDLQTALSANGYDAGNPDGIIGANTRKAIRAAQQ
ALGWPADGYPTVKLLESLQNR