Protein Info for PS417_24670 in Pseudomonas simiae WCS417

Annotation: DNA polymerase III subunit delta

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 345 TIGR01128: DNA polymerase III, delta subunit" amino acids 16 to 336 (321 residues), 386 bits, see alignment E=7e-120 PF06144: DNA_pol3_delta" amino acids 20 to 129 (110 residues), 65.7 bits, see alignment E=6.2e-22 PF21694: DNA_pol3_delta_C" amino acids 214 to 318 (105 residues), 32.2 bits, see alignment E=1.4e-11 PF14840: DNA_pol3_delt_C" amino acids 216 to 340 (125 residues), 60.6 bits, see alignment E=2.8e-20

Best Hits

KEGG orthology group: K02340, DNA polymerase III subunit delta [EC: 2.7.7.7] (inferred from 99% identity to pfs:PFLU5412)

Predicted SEED Role

"DNA polymerase III delta subunit (EC 2.7.7.7)" in subsystem DNA-replication (EC 2.7.7.7)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UHX7 at UniProt or InterPro

Protein Sequence (345 amino acids)

>PS417_24670 DNA polymerase III subunit delta (Pseudomonas simiae WCS417)
MKLAPAQLAKHLQGGLAPVYIVSGDDPLLCQEAADAIRTAARQQGFDERQVFSADASFDW
GTLLQAGASMSLFAEKRLLELRLPSGKPGDKGAAALMEYCSRPAEDTVLLISLPKLDGSA
QKTKWGKALVEGAHTQFIQIWPVDSNQLPQWIRQRLSQSGLSATQDAVELIAARVEGNLL
AAAQEIEKLKLMAEDGQITVETVQGAVADSARFDVFGLVDAILNGEPAHALRMLEGLRGE
GVEPPVILWALARELRVLANIALQYSQGTPLDKAFSQARPPVWDKRKPLMSKALQRHSAQ
RWAQLLLEAQRIDAQIKGQAAGSPWMSLSRLSLLMAGQRLTLPAE