Protein Info for PS417_24390 in Pseudomonas simiae WCS417

Annotation: peptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 438 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details TIGR01844: type I secretion outer membrane protein, TolC family" amino acids 17 to 435 (419 residues), 407.6 bits, see alignment E=3.1e-126 PF02321: OEP" amino acids 21 to 209 (189 residues), 87.3 bits, see alignment E=6e-29 amino acids 234 to 420 (187 residues), 107.6 bits, see alignment E=3.5e-35

Best Hits

Swiss-Prot: 57% identical to APRF_PSEAE: Alkaline protease secretion protein AprF (aprF) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K12538, outer membrane protein HasF (inferred from 95% identity to pfs:PFLU5356)

Predicted SEED Role

"ABC exporter for hemopore HasA, outer membrane component HasF" in subsystem Protein secretion by ABC-type exporters

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UCE4 at UniProt or InterPro

Protein Sequence (438 amino acids)

>PS417_24390 peptidase (Pseudomonas simiae WCS417)
MKALLFTVCFGCSSAVQALGLLDAYDLALRNDPTFQAAIQEREGGEENRAIGRAALLPNL
SWSYNNSRNASEVTAGDVTSERDYRSYASTLTLQQPLLDYEAYARFRQGTAQALMADERF
RGKSQELAVRVLNAYSQALLAQERIELSRAQKRAYAERLQLNDRLLKGGEGTRTDVLETQ
ARLSLALAEEIESQDAQDSALRELEAIIGQPLQIEELAPLTRQFEIPPLEPNRFETWREM
AMANNPELKSQHHALDVASYEVERKRAGHLPKVSLYATSRQTNSDSESSYNQKYDTNTVG
IQVSLPLFAGGGVSASTRQAANQLSQAQYELDAQTSATLVELRKQFNLNTSGAAKVRAYE
MAVSSATALVAATKKSVAGGERVNLDVLDAEQQLFTARRDLANARHAYLLARIQLKYYAG
LLNEQDLRALAGYFQPSA