Protein Info for GFF4735 in Xanthobacter sp. DMC5

Annotation: Chaperone SurA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 280 PF13145: Rotamase_2" amino acids 104 to 238 (135 residues), 51.6 bits, see alignment E=2.5e-17 PF13616: Rotamase_3" amino acids 124 to 223 (100 residues), 58.7 bits, see alignment E=1.3e-19 PF00639: Rotamase" amino acids 129 to 223 (95 residues), 78.2 bits, see alignment E=1.2e-25

Best Hits

KEGG orthology group: K03769, peptidyl-prolyl cis-trans isomerase C [EC: 5.2.1.8] (inferred from 54% identity to oca:OCAR_5047)

Predicted SEED Role

"Peptidyl-prolyl cis-trans isomerase PpiD (EC 5.2.1.8)" (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (280 amino acids)

>GFF4735 Chaperone SurA (Xanthobacter sp. DMC5)
MVEIVTLTAPRPAGRRPQEIRVDGVAVSRADIAREAQNHAAADPAAAWQAAAHALVVRQL
LLAEADRLGIAAVPEEDDEDRRETEEEAVIRALLEEEVKVPTADEDTCRRYFARNPALFR
TGDLYEVAHILIAADPTDAGARQAARDRAEALLTGLLSGAVAFETAAREVSACPSREVGG
SLGQIGRGQTVPEFETALAAMEPGALHPVPVETRYGFHIVRLAHRVEGRALPFEMVREAI
AGHLELSSWHAAMRQYVSLLIGRADIRGISMDGASSPLVQ