Protein Info for GFF4707 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Fe-S-cluster-containing hydrogenase components 2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 181 PF12800: Fer4_4" amino acids 10 to 22 (13 residues), 13 bits, see alignment (E = 5.5e-05) amino acids 87 to 102 (16 residues), 24.6 bits, see alignment (E = 9.5e-09) PF13247: Fer4_11" amino acids 55 to 104 (50 residues), 34.6 bits, see alignment E=8e-12 PF13187: Fer4_9" amino acids 58 to 104 (47 residues), 27.2 bits, see alignment E=1.5e-09 PF12838: Fer4_7" amino acids 58 to 103 (46 residues), 29.2 bits, see alignment E=4.9e-10 amino acids 88 to 151 (64 residues), 27.8 bits, see alignment E=1.3e-09 PF12837: Fer4_6" amino acids 81 to 103 (23 residues), 32.9 bits, see alignment (E = 1.9e-11) PF12797: Fer4_2" amino acids 82 to 101 (20 residues), 28.2 bits, see alignment (E = 5.5e-10) PF00037: Fer4" amino acids 83 to 104 (22 residues), 32 bits, see alignment (E = 3.5e-11)

Best Hits

Swiss-Prot: 96% identical to HYDN_ECO57: Electron transport protein HydN (hydN) from Escherichia coli O157:H7

KEGG orthology group: K05796, electron transport protein HydN (inferred from 98% identity to cko:CKO_04068)

Predicted SEED Role

"Fe-S-cluster-containing hydrogenase components 2" in subsystem Hydrogenases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (181 amino acids)

>GFF4707 Fe-S-cluster-containing hydrogenase components 2 (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MNRFIIADASKCIGCRTCEVACVVSHQENQDCASLTPETFLPRIHVIKGVNVSTATLCRQ
CEDAPCANVCPNGAISRDKGFVHVMQERCIGCKTCVVACPYGAMEVVVRPVVRNSGAGLN
VRAEKAEANKCDLCHHREAGPACMAACPTHALICVDRNKLEQLSAEKRRRAALDSTASLL
F