Protein Info for GFF4706 in Sphingobium sp. HT1-2

Annotation: Transcriptional regulator, LysR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 309 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF00126: HTH_1" amino acids 13 to 69 (57 residues), 72.6 bits, see alignment E=2e-24 PF03466: LysR_substrate" amino acids 94 to 299 (206 residues), 147.5 bits, see alignment E=3.6e-47

Best Hits

KEGG orthology group: None (inferred from 75% identity to azl:AZL_a04410)

Predicted SEED Role

"Transcriptional regulator, LysR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (309 amino acids)

>GFF4706 Transcriptional regulator, LysR family (Sphingobium sp. HT1-2)
MKEQIAFERLTGLIAFARVGSLGSFTAAARSLSISPSAVSKSVQRLEQTLGVPLITRTTR
SLALTPEGRDLHERALLLLRDAEEIEQMAITARSEPAGTLRIAASLPIGIHVLAPKLPAF
RERHPQVMVELRLNDQFVDLVEAGIDIAVRIGDLADTRLLARRLAPHRFCCFASPSYLAS
RGRPSHPDELVGHDTVNLRYQSSGQVLRWPFRVGDREVEIVPSSGIVMDASEALMAALAA
GGGVGISADFVAAPYVARGELVPVLSEFAVERHNITAVWPESRRTNPAVRAFLAHLQGTM
PRSKNIHPS